Before introducing an item into the PEC, what should be used to wipe it down?

Using 70% isopropyl alcohol (IPA) to wipe down items before introducing them into the primary engineering control (PEC) is crucial for maintaining a sterile environment. The 70% concentration is effective in killing a broad spectrum of microorganisms due to its optimal balance of alcohol and water. The water content in the solution aids in the penetration of the cell membrane of microbes, enhancing the antimicrobial activity without being overly harsh on surfaces or items being cleaned.

In a sterile compounding environment, especially within the PEC, maintaining aseptic conditions is vital to prevent contamination. 70% IPA evaporates quickly, leaving behind a dry surface that minimizes the risk of recontamination after cleaning. This method aligns with standard operating procedures for ensuring that all surfaces and items entering the PEC are properly disinfected before contact with sterile products.

Other options may not be suitable or effective for this purpose. For instance, bleach solutions can leave residues that can be harmful to sensitive equipment or solutions, while soap and water may not provide the rapid disinfection necessary in compounding settings. Alcohol wipes may be used for convenience but may not ensure the same level of disinfection over larger surfaces or items as the application of 70% IPA directly. Thus, wiping down items with